The Temperature Effect of Madeira Vine (Anredera Cordifolia) Leaf Oil Extraction and Its Characterization as An Additive in Health Supplement Product

The immune system is one of the most important things that need to be preserved in midst Corona Virus Disease 2019 (Covid-19) pandemic. Consuming components compounds contained Madeira vine (Binahong) leaf oil right and regular doses can way enhance system. This obtained by carrying out extraction process with reflux method on leaf. study aimed determine optimal time temperature process. was carried at 40, 50, 60 °C for 90, 100, 110 minutes. analyzed its density, solubility ethanol, chemical compounds. results showed highest yield (62.45% w/w) achieved using density ranges from 0.786-0.812 gr/ml. Analysis Gas Chromatography-Mass Spectrophotometry (GCMS) resulting extract several namely Neophytadiene; 2-Hexadecen-1-ol, 3,7,11,15-tetramethyl (phytol); Hexadecanoic Acid, methyl ester (methyl palmitate); 9,12-Octadecadienoic acid (Z,Z), linoleate); 9-Octadecenoic (Z), oleate); acid, ester;and Octadecanoic (Stearic acid).